Its not just can Dominick defend the takedown, Cejudo has to be in position to even be able to attempt the takedown. Can Cejudo close the distance so he can attempt for a takedown? Dom already has the height/reach. Dom has really good footwork. Dom is good at controlling range. The only good thing for Cejudo is that Dom doesn't really have the most power, so Cejudo will have to eat a few if he wants to get on the inside. But still, going for singles and doubles against Dom is difficult, his footwork allows him to control the range and get in an out. Nobody is questioning Cejudo wrestling ability/credentials. But in wrestling, both guys are trying to engage in grappling. In MMA, you don't have to engage in grappling. How do you use your wrestling against some you can't even put your hands on?
But lets say Cejudo is able to close the distance and push Dom against the cage. Can he even get Dom down? Dom is no slouch in wrestling either.
I just see Dom peppering Cejudo from the outside all night to a unanimous decision. Dom may even throw in a takedown near the end of round 5 just to make a point.
But then again, my analysis of Cruz is one where Dominick was an active fighter. He hasn't fought since 2016.