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Main Card (ESPN/ESPN+)
Michael Chiesa (17-4) vs. Neil Magny (24-7) (Welterweight)
Warlley Alves (13-4) vs. Mounir Lazzez (10-1) (Welterweight)
Isaac Villanueva (17-11) vs. Vinicius Moreira (9-4) (Light Heavyweight)
Roxanne Modafferi (25-17) vs. Viviane Araujo (9-2) (Women's Flyweight)
Matt Schnell (14-5) vs. Tyson Nam (20-11-1) (Flyweight)
Lerone Murphy (9-0-1) vs. Douglas Silva de Andrade (26-3) (Featherweight)
Preliminary Card (ESPN/ESPN+)
Omari Akhmedov (20-5-1) vs. Tom Breese (12-2) (Middleweight)
Ricky Simon (16-3) vs. Gaetano Pirrello (15-5-1) (Bantamweight)
Su Mudaerji (13-4) vs. Zarrukh Adashev (3-2) (Flyweight)
Dalcha Lungiambula (10-2) vs. Markus Perez (12-4) (Middleweight)
Francisco Figueiredo (11-3-1) vs. Jerome Rivera (10-3) (Flyweight)
Mike Davis (8-2) vs. Mason Jones (10-0) (Lightweight)
Victoria Leonardo (8-2) vs. Manon Fiorot (5-1) (Women's Flyweight)
Umar Nurmagomedov (12-0) vs. Sergey Morozov (16-4) (Bantamweight)
Other
- On December 30, Michael Chiesa and Neil Magny were moved to the main-event of this card. This gives both fighters 21 days to adjust from a 3-round fight to a 5-round fight.
- Dalcha Lungiambula vs. Isi Fitikefu was scheduled for this event. However, Fitikefu was removed due to an elbow injury and was replaced by Markus Perez on January 2.
- Omari Akhmedov and Tom Breese were originally scheduled to fight on January 16. However, they were moved to this UFC card just 4 days later due to "COVID-19 related issues."