International [Chinese COVID Vaccines News] After Sowing Propaganda Against mRNA Tech, China Realize They Needs It

[The_Renaissance]

Your original source of anti-mRNA propaganda is already back-pedaling. Time to catch up with your CCP commissars.

https://forums.sherdog.com/posts/165655767/

The two are not mutually exclusive.

Name one other vaccine that hasn't been smeared in the western media, other than Pfizer, in some shape or form? Go on. Name one. ONE.

Name one other vaccine manufacturer that sponsors 8/10 U.S news sources. Go on?

You're a fucking disgusting shill pal. That's all you are. I've had the Pfizer jab but I am refusing the booster, and they are a disgusting organisation.

 

[Arkain2K]

Hopes Are Rising for a Homegrown mRNA Vaccine in China
By Bloomberg News | November 10, 2021

​

China appears to be accelerating the development of its first homegrown mRNA Covid-19 vaccine, as Beijing’s authorization of the Pfizer Inc.-BioNTech SE shot remains in limbo.

The vaccine from Walvax Biotechnology Co. and Suzhou Abogen Biosciences Co. will be tested as booster shot in fully immunized adults as part of the pivotal trials that are already underway. The approach could give the companies a potential fast-track to the market in the world’s most populous country before those trials are fully completed.

The immunization uses the emerging mRNA technology that has proven dramatically effective in Western shots from Pfizer, BioNTech and Moderna Inc., triggering speculation that it may soon be enlisted as a powerful addition to the ongoing booster campaign in China.

The booster study will be part of the phase III trials that also seek to determine the vaccine’s efficacy against the original strain of the virus and the more infectious variants, a spokesperson for Kunming-based Walvax said. It may be easier for the companies to get a fast answer and access to a broad market for the vaccine as a booster than as a primary immunization.

“Boosters will undoubtedly be a significant opportunity for mRNA vaccines in China,” said Zhao Bing, a health care analyst with China Renaissance Securities HK Ltd. “It’s very likely the shot could be first given emergency authorization in China with data from the booster trial.”

The news buoyed investors, who sent shares of the Walvax soaring 13%, the most since late July, to 54.87 yuan on Wednesday. They were trading at 52.52 yuan at 1:12 p.m. in Shenzhen.

Access to a homegrown mRNA shot could limit demand for the Pfizer and BioNTech vaccine that uses the same technology and has been the backbone of vaccination across developed countries. Chinese drugmaker Shanghai Fosun Pharmaceutical Group Co. licensed the immunization and has sought, so far unsuccessfully, to bring it to the Chinese mainland.

“It will end up with a far smaller space in the market if the domestic mRNA vaccine is approved firsthand,” Zhao said.

Fosun lost as much as 6% in Hong Kong and declined 2.8% in Shanghai.

Fast Track

The booster shot approach means the local vaccine could be given in China before it gets definitive data from overseas trials on how effective it is at primary prevention for coronavirus. It would be mostly used as a booster for hundreds of millions of people already fully vaccinated with inactivated vaccines from state-owned Sinopharm and Beijing-based Sinovac Biotech Ltd.

China granted emergency authorization to the traditional immunizations in July 2020 when they were still being tested in the final phase III trials normally needed for approval. Chinese regulators issued conditional approval months later after they proved effective against infection, severe disease and deaths, though they are less potent than the novel mRNA vaccines.

Walvax said it couldn’t comment on the prospect of approval based on the vaccine’s booster trial. China’s drug regulator, the National Medical Products Administration, didn’t immediately respond to a request for comment.

The share rally may not last, given that the company has released scant data from its early human testing, said Mia He, Bloomberg’s senior health care analyst. The only data available on the shot so far is how it worked on mice, she said.

“Even if it states it is at phase III, it is difficult for us to judge whether it will be approved eventually,” He said.

https://www.bloomberg.com/news/arti...-rising-for-a-homegrown-mrna-vaccine-in-china

 

[DoctorsStoppage]

South Africa has no problem with the Omicron and they have vax rate of 20%.
You are being brainwashed as usual.
TOo much of your Fake News CNN

 

[Zazen]

Sinovac has shown to have virtually no negative side effects, the fearmongering is ridiculous because it is CHY-NA of course.

You guys really need to stop living in this childlike fantasy where everything from the West is unbiased and truthful and anything from China is nefarious, evil, and inferior. Both countries pump out propaganda but USA has demonized pretty much any vaccine developed abroad.

I have family members who took Sinovac and they are doing fine, its not nearly as ineffective as the West portrays it.

 

[EndlessCritic]

You guys really need to stop living in this childlike fantasy where everything from the West is unbiased and truthful and anything from China is nefarious, evil, and inferior. Both countries pump out propaganda but USA has demonized pretty much any vaccine developed abroad.

In China, the misinformation is being peddled by a dictatorship hellbent on ensuring the greatness of China.

In America, the misinformation is peddled by media hellbent on creating conflict to generate ratings.

 

[lifelessheap]

South Africa has no problem with the Omicron and they have vax rate of 20%.
You are being brainwashed as usual.
TOo much of your Fake News CNN

Omicron is literally a reason to celebrate.

 

[aerius]

Sinovac has shown to have virtually no negative side effects, the fearmongering is ridiculous because it is CHY-NA of course.

From their own research papers.
https://www.nature.com/articles/s41421-021-00329-3.pdf
Large-scale COVID-19 vaccinations are currently underway in many countries in response to the COVID-19 pandemic.
Here, we report, besides generation of neutralizing antibodies, consistent alterations in hemoglobin A1c, serum
sodium and potassium levels, coagulation profiles, and renal functions in healthy volunteers after vaccination with an
inactivated SARS-CoV-2 vaccine. Similar changes had also been reported in COVID-19 patients, suggesting that
vaccination mimicked an infection. Single-cell mRNA sequencing (scRNA-seq) of peripheral blood mononuclear cells
(PBMCs) before and 28 days after the first inoculation also revealed consistent alterations in gene expression of many
different immune cell types. Reduction of CD8+T cells and increase in classic monocyte contents were exemplary.
Moreover, scRNA-seq revealed increased NF-κB signaling and reduced type I interferon responses, which were
confirmed by biological assays and also had been reported to occur after SARS-CoV-2 infection with aggravating
symptoms. Altogether, our study recommends additional caution when vaccinating people with pre-existing clinical
conditions, including diabetes, electrolyte imbalances, renal dysfunction, and coagulation disorders.

There are no safe covid vaccines. Pick your poison. Literally.

 

[Arkain2K]

The two are not mutually exclusive.

Name one other vaccine that hasn't been smeared in the western media, other than Pfizer, in some shape or form? Go on. Name one. ONE.

Name one other vaccine manufacturer that sponsors 8/10 U.S news sources. Go on?

You're a fucking disgusting shill pal. That's all you are. I've had the Pfizer jab but I am refusing the booster, and they are a disgusting organisation.

What a load of mindless drivels. It's almost like you can't even fucking read the thread before spewing your garbage.

What the fuck does this public admission from the top Chinese health official about the Chinese vaccines' low efficacy, or the recent lab studies from the Chinese universities that confirmed it, or their move over to mRNA after spending an entire year convincing dumb-ass American anti-vaxxers that it's "untested and dangerous" have ANYTHING to do with the big bad "Western Media" or the evil Pfizer?

Do you actually have any dispute with their recent about-face ("self-smearing"?), or just here to cook up conspiracies?

Effectiveness of Chinese vaccines ‘not high’ and needs improvement, top health official says

The head of the Chinese Center for Disease Control and Prevention conceded that the efficacy of Chinese coronavirus vaccines is "not high" and that they may require improvements, marking a rare admission from a government that has staked its international credibility on its doses.

The comments on Saturday from George Gao come after the government has already distributed hundreds of millions of doses to other countries, even though the rollout has been dogged by questions over why Chinese pharmaceutical firms have not released detailed clinical trial data about the vaccines’ efficacy.

China has struck deals to supply many of its allies and economic partners in the developing world and boasted that world leaders — including in Indonesia, Pakistan and the United Arab Emirates — have taken the shots.

There have been signs that some countries remain skeptical: The UAE recently experimented with administering three shots of the Chinese Sinopharm vaccine, instead of two, over reports of low numbers of antibodies produced in some people, while Singapore has stockpiled but not used Sinovac shots.

China is “formally considering” options to change its vaccines to “solve the problem that the efficacy of the existing vaccines is not high,” Gao said at a conference in Chengdu.

Gao added that one possibility was to adjust the dosage or increase the number of doses. He said another option was to mix vaccines that are made with different technologies, in an apparent admission that China needs to develop messenger RNA vaccines using the revolutionary genetic technology that Western countries have harnessed.

Gao’s remarks, which appeared inadvertent and quickly spread through Chinese social media on Saturday before being mostly censored, marked a departure from the rosy assessments of Chinese-made vaccines by the government. By Sunday, Internet users were intentionally misspelling words in their posts while discussing Gao’s comments to keep them from being removed.

Sinopharm and Sinovac use a conventional method of producing vaccines that contains inactivated viruses, while other countries’ offerings, including those by Pfizer-BioNTech and Moderna, rely on a new technique that uses messenger RNA (mRNA) to stimulate an immune response.

The gap in efficacy between mRNA and inactivated vaccines has been observed broadly and among other countries’ shots, too. The overall efficacy of Johnson & Johnson’s one-shot vaccine is about 66 percent, compared with roughly 95 percent for the Pfizer-BioNTech and Moderna shots.

Chinese pharmaceutical companies are racing to catch up with the technology. Several Chinese companies are beginning trials, and executives say there could be a Chinese mRNA vaccine as early as this year.

The admission by the head of the Chinese CDC undercut other arms of the government, including its propaganda organs and diplomats, who have spent months touting Chinese vaccines as part of a soft power push while aggressively sowing doubt about Western alternatives by questioning the efficacy and safety of mRNA technology.

On Sunday, the Global Times, a state-run newspaper that has led the way in pushing theories about the coronavirus originating from outside China, hit back at the “hyped up” reports of Gao’s comments.

It quoted Gao as saying that his comments had been misunderstood and that he was speaking in general terms about how scientists, internationally, should improve their vaccine development.

“I was struck by what Gao said, not because it is significantly different from what we have already known but because it deviates from the official narrative on the effectiveness of Chinese and Western vaccines,” said Yanzhong Huang, a senior fellow at the Council on Foreign Relations. “I think he was trying to push for the approval of the use of Pfizer-BioNTech vaccines in China and/or the acceleration of the development of China’s own mRNA vaccines.”

https://www.washingtonpost.com/worl...fe3ab6-9a8f-11eb-8f0a-3384cf4fb399_story.html

Lastly, why would you even accuse anyone who got the Moderna shots to be "shilling for Pfizer" in a thread about actual Chinese Vaccine News? Or did your extended stay in goldenwolf's conspiracy chamber have dumbed you down to the point you can't even see how idiotic you sounds right now?

 

[DespicablePeep]

More propaganda.

https://www.globaltimes.cn/page/202104/1220774.shtml

Exclusive: Chinese CDC director refutes interpretation of ‘low protection rate of Chinese vaccines,’ says it confuses scientific vision he proposes to improve efficacy

https://www.globaltimes.cn/page/202104/1220774.shtml

What a load of mindless drivels. It's almost like you can't even fucking read the thread before spewing your garbage.

What the fuck does this public admission from the top Chinese health official about the Chinese vaccines' low efficacy, or the recent lab studies from the Chinese universities that confirmed it, or their move over to mRNA after spending an entire year convincing dumb-ass American anti-vaxxers that it's "untested and dangerous" have ANYTHING to do with the big bad "Western Media" or the evil Pfizer?

Do you actually have any dispute with their recent about-face ("self-smearing"?), or just here to cook up conspiracies?




Lastly, why would you even accuse anyone who got the Moderna shots to be "shilling for Pfizer" in a thread about actual Chinese Vaccine News? Or did your extended stay in goldenwolf's conspiracy chamber have dumbed you down to the point you can't even see how idiotic you sounds right now?

 

[Arkain2K]

@JDragon What previously seems like a win for Fosun is now a bust, because they didn't factor in the CCP's political angle when making the deal with BioNTech last year for the exclusive right to produce/distribute BioNTech's mRNA vaccines in China, Hong Kong, Macau, and Taiwan.

Fosun thought they would be making banks, but Beijing now simply pretend that their application for approval (filed over a year ago) doesn't exists, while pushing for a domestic mRNA vaccine backed by the Chinese military, one that's totally not "untested and dangerous" like the German mRNA "human experiment" that the CCP's official English-language mouthpiece Global Times spent a year spreading all kinds of rumors about (much of which were promptly swallowed whole by the ignorant anti-vaxxers on Sherdog).

Fosun’s Bet on BioNTech Vaccine for China Fails to Pay Off
Bloomberg News | December 12, 2021

Guo Guangchang​

As Covid-19 started spreading in Wuhan early last year, Chinese billionaire Guo Guangchang’s drugmaker appeared to have scored a big win: A partnership with Germany’s BioNTech SE, which went on to produce with Pfizer Inc. one of the world’s most successful vaccines against the coronavirus.

Yet almost a year later, the shot is yet to be approved in mainland China, and in recent weeks Beijing has thrown its heft behind a homegrown mRNA vaccine, allowing China’s Walvax Biotechnology Co. to test its own experimental shot as a booster. The developments are raising new questions about whether the U.S.-German vaccine, licensed for the potentially lucrative Greater China region by Guo’s Shanghai Fosun Pharmaceutical Group Co., will ever be used on the mainland, where President Xi Jinping’s administration has backed a nationalist agenda on all fronts, including in the fight against the virus.

The delayed approval is the latest sign of how vulnerable Chinese tycoons -- and their foreign partners -- are to Beijing’s political dictats. It also highlights the uncertain outlook for global drugmakers in China, the world’s second biggest pharmaceutical market and a big one for Covid-19 products. More than 1 billion Chinese have been inoculated with the traditional shots made by Sinovac Ltd. and Sinopharm Group even though they have been found to be less effective than mRNA ones in scientific studies.

It’s hard to tell when, if ever, the Pfizer-BioNTech vaccine will be approved for mainland China since regulators haven’t publicly said why it’s being held back, analysts say.

The Chinese market could fall out of reach for international pharmaceutical firms if approvals for vaccines and medicines intended for Covid are made “a political issue, rather than an economic or biological one.” said Zhao Bing, a senior analyst who oversees health-care research at China Renaissance Securities HK Ltd. Given the domestic competition, the prospects in China for the shot may be limited even if it is eventually approved for use in the mainland, he said.

“How much market share can Fosun grab?” said Zhao.“I don’t know, but it’s certainly not looking optimistic.”

The uncertainty is a blow to the ambitions of Guo, 54, who in recent years has increasingly made health care a key area of focus for his conglomerate. Fosun Pharma’s shares are now more than 40% below their August high. Guo’s own net worth, meanwhile, has plunged to $3.5 billion from this year’s peak of $4.6 billion amid the selloff and as China’s economic slowdown and intermittent Covid resurgences have hurt the retail and tourism arms of his conglomerate, Fosun International Ltd.

In an emailed response to questions, Fosun Pharma said its collaboration with BioNTech “has always been supported by relevant regulatory authorities.” The clinical trials and approval process are progressing in accordance with China’s laws, the company said.

Still, the shot has already been widely approved around the world for months. Pfizer -- which has the rights to market it outside of Fosun’s distribution area of mainland China, Hong Kong, Taiwan and Macau -- is pulling in billions in revenue from the vaccine. While Fosun has sold it in Hong Kong, Taiwan and Macau, where it’s been green-lit by regulators, a BioNTech representative said the application for the vaccine’s use on the mainland is still ongoing.

China’s regulator, the National Medical Products Administration and the State Council Information Office didn’t immediately respond to a request for comment.

Fosun was required to pay 125 million euros ($141 million) to BioNTech before the end of 2020 as an initial payment to secure 100 million doses for mainland China in 2021. Some of those shots -- with labels featuring the vaccine’s brand name in simplified Chinese -- eventually reached Taiwan as donations from its local chipmaking giants and charities, who purchased them from Fosun.

Meanwhile, Fosun also agreed to invest $100 million in a joint venture with BioNTech to manufacture the vaccine in China. The plant, once completed with technology transfers and manufacturing know-how from BioNTech, was supposed to churn out 1 billion doses of the shot annually. But the JV isn’t currently operating with doses for region coming from BioNTech’s plant in Germany.

The vaccine setback comes at a time when China has curbed the ascent of some of its most powerful tycoons, derailing the IPO of Jack Ma’s Ant Financial and placing restrictions on the gaming business of Pony Ma’s Tencent Holdings Ltd. In the pharmaceutical space, Chinese leaders now appear eager to prove the country’s prowess at vaccine-making, encouraging sales of local shots around the world as a way of increasing Beijing’s geopolitical heft.

Walvax’s shot, being co-developed with local biotech Suzhou Abogen Biosciences Co. and the Chinese military, is now being tested in final-stage trials in countries including Mexico and Indonesia, and the results are expected as soon as the end of this year.

“China doesn’t have an mRNA vaccine right now. When it does, it’d better be a domestic one, so that it shows the country is just as capable of pulling it off,” said Mia He, senior health-care analyst at Bloomberg Intelligence.

https://www.bloomberg.com/news/arti...-on-pfizer-vaccine-for-china-fails-to-pay-off

 

[Yehudim]

More propaganda.

https://www.globaltimes.cn/page/202104/1220774.shtml

Exclusive: Chinese CDC director refutes interpretation of ‘low protection rate of Chinese vaccines,’ says it confuses scientific vision he proposes to improve efficacy

https://www.globaltimes.cn/page/202104/1220774.shtml

I see you've taken the stupid bus along with another person in this thread by posting literal (I do mean literal) Chinese propaganda while accusing others of using propaganda.

 

[DespicablePeep]

I see you've taken the stupid bus along with another person in this thread by posting literal (I do mean literal) Chinese propaganda while accusing others of using propaganda.

Its the actual doctor denying he made those claims. Propaganda is twisting translations son.

Retard bus awaits you

 

[The Audience]

People immunised with Coronavac do not see the same effect against Omicron variant after a 3rd dose boost as those with 2 mRNA vaccines previously; a 4th dose (of mRNA) may be required to achieve a similar neutralising antibody response:



Interestingly, prior infection made 'no difference' to the antibody response after an mRNA booster re. Omicron neutralisation in the same way that is seen with the mRNA vaccines: thought to be related to how the mRNA vaccines interact with long-term immune cells.

 

[Arkain2K]

New Chinese Covid-19 vaccine targeting unspecified "major variants" is approved in UAE
UAE approves it for emergency use as a booster after study involving people already vaccinated with two doses of Sinopharm’s previous vaccine
By Zhuang Pinghui | 29 Dec, 2021

A new Covid-19 vaccine from Chinese firm Sinopharm that it says protects against multiple variants has been approved for emergency use in the United Arab Emirates.

China National Biotec Group (CNBG), the vaccine development arm of Sinopharm, said on Monday that the vaccine would be provided as a booster for those who had previously taken its vaccines, but did not state which variants the vaccine protected against.

The group’s previous vaccine was the inactivated type, made by killing – or inactivating – the whole virus to destroy its disease-producing capacity. Its new vaccine is based on a different technology called recombinant protein, which involves genetically modifying the coronavirus.

“The UAE Ministry of Health and Prevention approved the emergency use of Sinopharm recombinant protein vaccine, the world’s first second-generation Covid-19 vaccine,” the statement said. “It has broad-spectrum protection against multiple variants.”

The vaccine had been given to nearly 2,000 people in the UAE during a study, with preliminary results indicating it was “safe and well tolerated, and can stimulate high levels of neutralising antibodies against the prototype strain and major variants”, it said.

The vaccine is not in use in China, but CNBG announced in September that it had developed a second-generation protein vaccine targeting not only the original virus but also other variants including Delta. The world’s first generation of vaccines had based their designs solely on the original strain of the virus.

A recombinant protein Covid-19 vaccine contains a genetically modified spike protein from the coronavirus to trigger an immune response from the body without making people sick. A further substance is usually added to boost its performance. The method is commonly used in vaccines against other diseases, such as influenza.

The new Sinopharm vaccine is based on a part of the coronavirus spike protein called the receptor binding domain, which docks on the host cell to initiate the process of infection.

In a paper published this month in Frontiers of Medicine, a peer-reviewed journal from the Chinese education ministry, CNBG researchers compared two groups of participants, one given a booster of the new protein vaccine and the other given a booster of the inactivated vaccine, with both groups having had two doses of inactivated vaccine more than six months earlier.

They found that the levels of protective antibodies were more than three times higher in those who had the new protein vaccine as a booster. The exploratory study was small, involving only five participants per group, the authors said.

The UAE ministry said in a statement that its approval for emergency use had followed “strict monitoring and evaluation of the data of the study conducted in the UAE”.

The study included people who were previously vaccinated with two doses of Sinopharm’s inactivated vaccine. All developed protective antibodies after having the new vaccine and no side-effects were recorded, the UAE ministry said.

The new vaccine will be produced and distributed by Hayat Biotech, a joint venture between UAE firm G42 and Sinopharm, and will be available to the public as a booster dose starting in January. The venture has been producing Sinopharm’s previous Covid-19 vaccine locally under the name Hayat-Vax.

https://amp.scmp.com/news/china/sci...-covid-19-vaccine-targeting-multiple-variants

 

[Arkain2K]

Chinese flock to Hong Kong to get BioNTech/Pfizer mRNA vaccine shots
Travel packages also advertised in Macau as interest grows in mRNA vaccines unavailable on mainland
By Helen Davidson | Jan 13, 2023



Private services offering Chinese travellers access to mRNA vaccines are attracting droves of mainlanders to Hong Kong and Macau seeking a booster shot that their government has refused to approve.

As part of its dismantling of the country’s zero-Covid policy last month, China’s government also lifted quarantine and other border restrictions. It prompted a wave of interest in overseas travel, particularly for the upcoming lunar new year holiday later this month. However, there also appears to be a large contingent chasing the mRNA bivalent vaccines.

Throughout the pandemic the Chinese government has allowed only domestically produced vaccines for its citizens, refusing to approve foreign-made jabs. Health experts and medical studies have raised concerns about the efficacy of China’s vaccines, which use an inactivated virus, compared with the mRNA vaccines available elsewhere.

The appetite for the overseas vaccine is difficult to quantify, but a rash of services offering travel packages and self-funded shots in Hong Kong and Macau have sprung up in recent weeks. Clinics in Thailand and Singapore have also reported increased interest from Chinese travellers.

The BioNTech/Pfizer mRNA vaccine is free to residents of Hong Kong and Macau. On Thursday, the Hong Kong government announced it would no longer provide free shots of any vaccine for non-residents from next week, in response to the “recent increase in demand”. Prices for privately funded shots for non-residents in Hong Kong range from about HK$1,300 to $2,000 (£136-£209).

On Chinese social media platforms, C3Hong Kong Life, a travel service for mainlanders, advertised bookings from 8 January for people to travel to Hong Kong and get the shot for HK$1,680.

It offered a full vaccination travel package providing “expert guidance, vaccine appointments, round-trip itinerary arrangements, border pickup and other services”.

The Macau University of Science and Technology has a website for people to book a vaccine shot for prices beginning at HK$1,360. All appointments – about 100 a day – are booked until mid February.

Staff at one cross-border travel agency, xBorder, said they had facilitated “a lot” of people travelling to Macau – where entry restrictions were looser than Hong Kong – in the last quarter of 2022, and were getting a lot of interest from people wanting to go to Hong Kong.

However, the staff member added that many people infected during China’s recent outbreak had to wait three months before they could get a vaccine shot. Some Chinese cities have reported infection rates of 70-90% in the last month.

One woman posted on Weibo that her father had recently had Covid, and she feared his underlying health conditions would worsen after another bout. “Although he has recovered now, he is still very afraid of his secondary infection,” she said. After seeing the availability of the bivalent vaccine in Hong Kong, she said she planned to take her whole family to get boosted.

Shanghai Fosun Pharmaceutical Co, the China-region distributor of the BioNTech/Pfizer vaccine, is also promoting “go to Hong Kong, get the vaccination”. In December, the company’s vaccine was registered as a pharmaceutical product, widening availability in Hong Kong, and was granted approval for provision to visitors.

Earlier this week, the Financial Times reported a Chinese state-owned bank, China Citic Bank International, was offering new mainland customers a free mRNA shot if they made a deposit of HK$4m.

Online, some Chinese people expressed support for taking the domestic vaccines, with some suspicious of foreign-made products. Others vented frustration that access to the bivalent vaccine required travel and personal expense.

“If it is produced in the mainland, why can’t it be sold in the mainland,” said one commenter.

“After 40 years of ‘reform and opening up’, mainlanders are still living in isolated islands,” said another.

A popular medical blogger on Weibo, Dr Xu Chao, last week urged people to get vaccinated, advising of the benefits of the bivalent mRNA shot.

“Obviously, the bivalent vaccine provides additional protection for people who have only been vaccinated with the monovalent vaccine in the past,” Xu wrote. “Considering that many people in China have been away from the third dose for a long time, and the risk of recent infection is high, it is extremely important to obtain real and effective protection as soon as possible.”

https://www.theguardian.com/world/2...-get-private-covid-booster-shots-mrna-vaccine

 

[Arkain2K]

Chinese-made mRNA vaccine starts trial production
By Reuters | January 6, 2023

SHANGHAI, Jan 7 (Reuters) - China's CanSino Biologics Inc (6185.HK) has entered "test production phase" for its COVID-19 mRNA booster vaccine, the company said in a post on its social media account late on Thursday.

The vaccine, known as CS-2034, targets new Omicron variants of the virus, which are responsible for the vast majority of infections that have swept across China since the country began dismantling strict COVID curbs last month.

Until now, China has relied on nine domestically-developed COVID vaccines approved for use, including inactivated vaccines, but none have been adapted to target the highly-transmissible Omicron variant and its offshoots that are currently in circulation.

The CanSino booster vaccine is one of China's first home-grown potential vaccines based on mRNA technology similar to that employed in vaccines produced internationally by Pfizer-BioNTech and Moderna.

On Thursday, CanSino also reported "positive" interim data from a mid-stage clinical trial in a filing to the Hong Kong stock exchange.

According to CanSino, the first phase of its mRNA vaccine production could produce 100 million doses.

https://www.reuters.com/world/china/chinese-made-mrna-vaccine-starts-trial-production-2023-01-07/

 

[Arkain2K]

China's CanSino confident its mRNA COVID vaccine as good as Moderna, Pfizer shots
By Natalie Grover and Sophie Yu | February 3, 2023

LONDON, Feb 3 (Reuters) - CanSino Biologics Chief Executive Yu Xuefeng said on Friday he was confident his company's experimental COVID-19 vaccine using messenger RNA (mRNA) technology was as good as shots from Moderna and Pfizer-BioNTech.

As the COVID-19 pandemic evolves in China after the country abandoned its zero-COVID policy in December, domestic companies like CanSino are racing to develop mRNA COVID vaccines.

The country - which experienced a wave of infections across its 1.4 billion population after the sudden relaxation of COVID restrictions - has so far declined to use mRNA vaccines from abroad, and has yet to approve a domestic one that uses the technology.

Approved vaccines in China are widely considered less effective than the Moderna Inc and Pfizer Inc-BioNTech SE mRNA shots.

Yu acknowledged that it was not possible to directly test the CanSino vaccine versus the Moderna or Pfizer-BioNTech shots in a head-to-head trial because they were not available in China.

"But just based on published data...I'm confident our product is as good as the already launched mRNA vaccines," he told Reuters in an interview.

In January, CanSino reported "positive" interim data from its experimental COVID-19 mRNA booster vaccine, CS-2034, in a mid-stage clinical trial.

When asked whether Chinese authorities were keen to have a homegrown mRNA vaccine, Yu said there was not much public information on what was going on.

"But I will say, from the technology perspective, any product - as long as you meet the regulatory requirements - there's no reason to not allow to enter into the market."

CanSino is currently in discussion with Chinese regulators around the protocol for a late-stage study for CS-2034 - and the trial will definitely be conducted this year, Yu said.

If the vaccine is approved, the company is working on ways to reduce the costs of making and deploying its mRNA vaccine, he said, noting that it will definitely be cheaper than the roughly $120 list price per dose Pfizer is hoping to charge in the United States later this year.

Although mRNA technology is more malleable and easier to tweak to address new variants versus traditional vaccine approaches, mRNA vaccines typically require more expensive ultra-cold storage.

However, researchers have made some strides in making sure formulations remain stable at somewhat higher temperatures.

https://www.reuters.com/business/he...vaccine-good-moderna-pfizer-shots-2023-02-03/

 

[Eusung]

Possibly the saddest thread bump by an OP. Talk about doubling down on a freakin 2020 thread that aged horribly.

 

[Greco_Wiz]

Omicron is literally a reason to celebrate.

What a mindless thing to say.

 

[Yehudim]

Possibly the saddest thread bump by an OP. Talk about doubling down on a freakin 2020 thread that aged horribly.

What does this even mean? He's just posting updates to the story.