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Main Card (ESPN+)
Rose Namajunas (8-3) vs. Jessica Andrade (19-6) (Women's Strawweight Championship)
Jared Cannonier (11-4) vs. Anderson Silva (34-9) (Middleweight)
Jose Aldo (28-4) vs. Alexander Volkanovski (19-1) (Featherweight)
Thiago Alves (23-13) vs. Laureano Staropoli (8-1) (Welterweight)
Irene Aldana (9-4) vs. Bethe Correia (10-3-1) (Women's Bantamweight)
Preliminary Card (ESPN)
Antonio Rogerio Nogueira (23-8) vs. Ryan Spann (15-5) (Light Heavyweight)
Thiago Moises (11-3) vs. Kurt Holobaugh (17-6) (Lightweight)
Warlley Alves (12-3) vs. Sergio Moraes (14-4-1) (Welterweight)
B.J. Penn (16-13-2) vs. Clay Guida (34-18) (Lightweight)
Preliminary Card (UFC Fight Pass)
Luana Carolina (5-1) vs. Priscila Cachoeira (8-2) (Women's Flyweight)
Raoni Barcelos (13-1) vs. Carlos Huachin (10-3-1) (Bantamweight)
Talita Bernardo (6-3) vs. Viviane Araujo (6-1) (Women's Flyweight)
Other
- A bantamweight bout between Talita Bernardo and Jessica-Rose Clark was scheduled at the event. However, it was reported on April 3, 2019 Clark pulled out of the bout citing injury and was replaced by promotional newcomer Melissa Gatto. In turn, Gatto was pulled from the fight in the days leading up to the event and replaced by Viviane Araujo on May 8.
- A flyweight bout between Luana Carolina and Yanan Wu was scheduled at the event. However it was reported on April 22, 2019 that Wu pulled out of the bout due to injury and she was replaced by Priscila Cachoeira on April 23.
- A bantamweight bout between Said Nurmagomedov and Raoni Barcelos at the event. However, it was reported on May 1, 2019 that Nurmagomedov pulled out of the bout for undisclosed reason and he was replaced by newcomer Carlos Huachin that same day.
- A lightweight bout between Carlos Diego Ferreira and Francisco Trinaldo was scheduled to take place as part of the main card. However, Ferreira was forced out of the bout on weigh-in day as he was deemed medically unfit due to a weight cutting issue. As a result, the bout was cancelled.
