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Main Card (ESPN+)
Thiago Santos (21-7) vs. Glover Teixeira (31-7) (Light Heavyweight)
Andrei Arlovski (29-19) vs. Tanner Boser (19-6-1) (Heavyweight)
Raoni Barcelos (15-1) vs. Khalid Taha (13-2) (Bantamweight)
Giga Chikadze (11-2) vs. Jamey Simmons (7-2) (Featherweight)
Claudia Gadelha (18-4) vs. Yan Xiaonan (12-1) (Women's Strawweight)
Preliminary Card (ESPN+)
Trevin Giles (12-2) vs. Bevon Lewis (7-2) (Middleweight)
Marcos Rogerio de Lima (17-6-1) vs. Alexander Romanov (12-0) (Heavyweight)
Darren Elkins (24-9) vs. Luiz Eduardo Garagorri (13-1) (Featherweight)
Max Griffin (15-8) vs. Ramiz Brahimaj (8-2) (Welterweight)
Gustavo Lopez (11-5) vs. Anthony Birchak (16-6) (Bantamweight)
Other
- A bantamweight bout between Khalid Taha and Jack Shore was expected to take place at the event. However, Shore was removed from the bout in late-October due to undisclosed reasons and replaced by Raoni Barcelos on October 28.
- Felipe Colares pulled out of a scheduled bantamweight bout against Gustavo Lopez during fight week as he tested positive for COVID-19, and he was replaced by Anthony Birchak on November 4.